After 72 h, the animals were killed and the colon was dissected out for microscopic, clinical evaluation, histopathological study and biochemical estimation. It is well known to Ayurvedic medicine because of its curative and lenitive properties. Pterocarpus marsupium Roxb., a medicinal plant, known for its anti-oxidant and anti-diabetic activity is a rich source of phytochemicals with antihyperglycemic and antihyperlipidemic … Pterocarpus marsupium may lower blood sugar through an unrelated pathway of that of insulin. The herb improved the body weight of diabetic animals. Good amount of total phenolics and total flavonoids in small branches and HPTLC profile with many bands indicates that small branches may also have potential active constituents and may be studied for various pharmacological activities. in a neonatal rat model. Among many medications and other alternative medicines, several herbs have been known to cure and control diabetes; additionally they have no side effects. Histopathological studies support the effect. Detaillierte Informationen im Zusammenhang mit … Treatment of Diabetes: As discussed above, one of the most popular ways in which Pterocarpus marsupium … Termed biologically as Pterocarpus marsupium… Aqueous extract of the wood of this plant has a long history to be used in treatment of diabetes mellitus. Pterocarpus marsupium reduces blood sugar level, cholesterol and triglycerides. The rats were divided into five groups, each having six rats. The standard parameters of small branches of P. marsupium have not been prepared yet. Pterocarpus marsupium Roxb., is a deciduous tree commonly grows in Sri Lanka and India [1]. The treatment also normalized the altered antioxidant enzyme levels (LPO, SOD and GSH). Type 2 diabetes was induced by administering streptozotocin (90 mg/kg, i.p.) Pterocarpus marsupium is a medicinal plant used in Ayurvedic system of medicine to control blood sugar and strong antidiabetic. Vijaysar continues to be used for diabetics … So work is carried out to establish preliminary physicochemical and phytochemical standards of small branches of P. marsupium. However, its possible role in diabetic complications is not evaluated yet. The alcoholic extract of P. marsupium was evaluated for advanced glycation-end-products formation, erythrocyte sorbitol accumulation and rat kidney aldose reductase enzyme inhibition at the concentration of 25–400 μg/ml using in-vitro bioassays. Blood glucose level, serum triglycerides, total cholesterol, HDL cholesterol and LDL cholesterol were evaluated in gabapentin induced diabetic rats. The medicinal plants, besides having natural therapeutic values against various diseases and considerable works have been done on these plants to treat diabetes mellitus, describes that the antidiabetic activity of medicinal plants is due to the presence of phenolic compounds, flavonoids, terpenoids, coumarins and other constituents which show reduction in blood glucose levels. It is also considered as a potential source of drugs used as an anti-inflammatory, nootropic, astringent, anthelmintic, hypolipidemic, hepatoprotective, anti-ulcer, antioxidant, cardiotonic activities. In conclusion, the results suggested a No-Observed-Adverse-Effect-Level (NOAEL) of 200 mg/kg bwt/day in rats after oral administration, implying 3'-HPT did not exhibit any toxicity under the study conditions employed. It seems that there are different cellular binding sites for insulin and Pterocarpus marsupium, which … Two fractions (2.5% and 5%) of extract from the medicinal plant Pterocarpus marsupium … International Journal of Basic & Clinical Pharmacology. One of the most important benefits of Vijaysar tree or Pterocarpus Marsupium is to control diabetes. Uses : The heartwood of pterocarpus marsupium is astringent, bitter acrid, anti inflammatory, anthelmintic and anodyne. A REVIEW-PHYTOMEDICINES USED IN TREATMENT OF DIABETES, Evaluation of 90 day repeated dose oral toxicity and reproductive/developmental toxicity of 3'-hydroxypterostilbene in experimental animals, Evaluation of effect of alcoholic extract of heartwood of Pterocarpus marsupium on in vitro antioxidant, anti-glycation, sorbitol accumulation and inhibition of aldose reductase activity, Phytochemistry and pharmacological activities of Pterocarpus marsupium: a review, Pharmacology of Pterocarpus marsupium Roxb, Evaluation of the protective effect of Pterocarpus marsupium on acetic acid-induced ulcerative colitis in rats, Bijayasaline: A New C-Glucosyl--hydroxydihydrochalcone from the Heartwood of Bijayasal (Pterocarpus marsupium), Hypoglycaemic effect of Pterocarpus marsupium, A Study on Hypoglycemic properties of Pterocarpus marsupium Roxb, Pterocarpus marsupium: A valuable medicinal plant in diabetes management, Hypolipidemic activity of Pterocarpus marsupium in streptozotocin induced diabetes, Antidiabetic effect of Pterocarpus marsupium seed extract in gabapentin induced diabetic rats, In vitro evaluation of antibacterial activity of pterocarpus marsupium roxb. Also the phytoextract at the concentration of 10–320 μg/ml was evaluated for its antioxidant potential by in-vitro antioxidant assays which includes, determination of total phenol content; reducing power assay; nitric oxide scavenging activity; superoxide radical scavenging activity; total antioxidant capacity; total flavonoid content; DPPH scavenging activity; and hydrogen peroxide scavenging activity. The present study explores the possible role of alcoholic extract of heartwood of P. marsupium in the treatment of long-term diabetic complications. It has a long history of numerous traditional and ethno-botanical applications in diverse cultures. (family Fabaceae) is widely used as a traditional medicine to treat various diseases, including diabetes. It is considered magical for diabetes. Buy Panchaveda Pterocarpus Marsupium 400 mg Extract (120 Veg Capsules) Organic Natural Ayurvedic Herbal Diabetes Blood Sugar Support Supplement, Vijaysar Indian Kino Tree Helps Bad … The conditions commonly treated by pterocarpus in the Ayurveda system include diabetes, inflammation and bleeding. The present investigation suggests that the phytoextract showed prominent antioxidant, antiglycation property and, inhibited accumulation of sorbitol and ALR enzyme, thus promising a beneficial role in reducing/delaying diabetic complications. It also lowers the symptoms of diabetes such as frequent urination, over eating, regular thirsts, and burning pains in limbs. It is now considered as a valuable source of unique natural products for development of medicines against various diseases and for the development of industrial products. Aqueous extract of P. marsupium at doses 100 and 200 mg/kg, decreased the fasting and postprandial blood glucose in type 2 diabetic rats. 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